Publications

There are numerous scientific publications describing use of the Emphasys Zephyr® Endobronchial Valve system.* These articles range from proof of concept studies to single center and multi-center series. A current bibliography grouped by topic is listed below for your reference and convenience only and does not imply affiliation or endorsement by Emphasys.

Emphysema

  1. Bouros, D. and M.E. Froudarakis, Bronchoscopic Lung Voume Reduction: A Window for the Future? Respiration, 2004. 71: p. 214-215.
  2. Brown, M.S., et al., CAD in clinical trials: Current role and architectural requirements. Computerized Medical Imaging and Graphics, 2007. 31: p. 332‑337.
  3. Cetti, E.J., A.J. Moore, and D.M. Geddes, Collateral ventilation. Thorax, 2006. 61: p. 371-373.
  4. de Oliveira, H., et al., Transbronchoscopic Pulmonary Emphysema Treatment: 1-Month to 24-Month Endoscopic Follow-up. Chest, 2006. 130(1): p. 190-199.
  5. Fann, J.I., G.J. Berry, and T.A. Burdon, Bronchoscopic Approach to Lung Volume Reduction Using a Valve Device. J Bronchol, 2003. 10: p. 253-259.
  6. Garzon, J.C., et al., Video-assisted thoracic surgery lung resection after endobronchial valve placement. J Thorac Cardiovasc Surg, 2006. 131: p. 501-502.
  7. Hillier, J.E., T.P. Toma, and C.E. Gillbe, Bronchoscopic Lung Volume Reduction in Patients with Severe Emphysema: Anesthetic Management. Anesth Analg, 2004. 99(6): p. 1610-1614.
  8. Hopkinson, N.S., Bronchoscopic lung volume reduction: indications, effects and prospects. Curr Opin Pulm Med, 2007. 13: p. 125-130.
  9. Hopkinson, N.S., et al., Effect of Bronchoscopic Lung Volume Reduction on Dynamic Hyperinflation and Exercise in Emphysema. Am. J. Respir. Crit. Care Med., 2005. 171(5): p. 453-460.
  10. Lunn, W.W., Endoscopic Lung Volume Reduction Surgery. Chest, 2006. 129: p. 504-506.
  11. Maxfield, R.A., New and Emerging Minimally Invasive Techniques for Lung Volume Reduction. Chest, 2004. 125(2): p. 777-783.
  12. McKenna, R.J., Bronchial Blockers for Lung Volume Reduction Surgery: Where Are We and Where Are We Going? J Bronchol, 2005. 12(2): p. 67-68.
  13. Noppen, M., et al., Successful Treatment of a Giant Emphysematous Bulla by Bronchoscopic Placement of Endobronchial Valves. Chest, 2006. 130(5): p. 1563‑1565.
  14. Polkey, M.I. and N.S. Hopkinson, Bronchoscopic lung volume reduction. Eur Respir Rev, 2006. 15(100): p. 99-103.
  15. Salanitri, J., et al., 133Xenon ventilation scintigraphy applied to bronchoscopic lung volume reduction techniques for emphysema: relevance of interlobar collaterals. Internal medicine Journal, 2005. 35: p. 97-103.
  16. Snell, G., et al., The Potential for Bronchoscopic Lung Volume Reduction Using Bronchial Prostheses: A Pilot Study. Chest, 2003. 124(3): p. 1073-1080.
  17. Strange, C., et al., Design of the Endobronchial Valve for Emphysema Palliation Trial (VENT): a non-surgical method of lung volume reduction. BMC Pulmonary Medicine 2007 7:10.
  18. Toma, T., et al., Bronchoscopic volume reduction with valve implants in patients with severe emphysema. Lancet, 2002. 361: p. 931-933.
  19. Toma, T., et al., Methodological Aspects of Bronchoscopic Lung Volume Reduction with a Proprietary System. Respiration, 2003. 70: p. 658-664.
  20. Toma, T.P., D.M. Geddes, and P.L. Shah, Brave new world for interventional bronchoscopy. Thorax, 2005. 60: p. 180-181.
  21. Venuta, F., et al., Bronchoscopic Lung-Volume Reduction With One-Way Valves in Patients With Heterogenous Emphysema. Ann Thorac Surg, 2005. 79(2): p. 411-417.
  22. Venuta, F., et al., Bronchoscopic procedures for emphysema treatment. European Journal of Cardio-thoracic Surgery, 2006. 29: p. 281-287.
  23. Wan, I.Y., et al., Bronchoscopic Lung Volume Reduction for End-Stage Emphysema: Report on the First 98 Patients. Chest, 2006. 129(3): p. 518-526.
  24. Yim, A.P., et al., Early results of endoscopic lung volume reduction for emphysema. J Thorac Cardiovasc Surg, 2004. 127(6): p. 1564-1573.

Air Leaks

  1. Anile, M., et al., Treatment of persistent air leakage with endobronchial one-way valves. The Journal of Thoracic and Cardiovascular Surgery, 2006. 132(3): p. 711-712.
  2. De Giacomo, T., et al., Successful treatment with one-way endobronchial valve of large air-leakage complicating narrow-bore enteral feeding tube malposition. Eur J Cardiothorac Surg, 2006. 30(5): p. 811-812.
  3. Fann, J.I., G.J. Berry, and T.A. Burdon, The use of endobronchial valve device to eliminate air leak. Respir Med. 2006;100(8):1402-6. Epub 2006 Jan 11.
  4. Feller-Kopman, D., et al., Use of a Removable Endobronchial Valve for the Treatment of Bronchopleural Fistula. Chest, 2006. 130(1): p. 273-275.
  5. Ferguson, J.S., K. Sprenger, and T. Van Natta, Closure of a Bronchopleural Fistula Using Bronchoscopic Placement of an Endobronchial Valve Designed for the Treatment of Emphysema. Chest, 2006. 129(2): p. 479-481.
  6. Mitchell, K., T. Boley, and S. Hazelrigg, Endobronchial Valves for Treatment of Bronchopleural Fistula. Ann Thorac Surg, 2006. 81(3): p. 1129-1131.
  7. Snell, G., et al., Occlusion of a Broncho-Cutaneous Fistula With Endobronchial One-Way Valves. Ann Thorac Surg, 2005. 80(5): p. 1930-1932.
  8. Toma, TP, et al., Reduction of persistent air leak with endoscopic valve implants. Thorax, 2007. 62(9): 829-32.

Native Lung Hyperinflation in Transplant Patients

  1. Crespo, M.M., et al., Use of Endobronchial Valves for Native Lung Hyperinflation Associated with Respiratory Failure in a Single-Lung transplant Recipient for Emphysema. Chest, 2007. 131: p. 214-216.